|Full Name||transferrin receptor 2|
|Product Description||Rabbit Polyclonal antibody to TFR2 (transferrin receptor 2)|
|Background||This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq]|
|Synonyms||HFE3 antibody, MGC126368 antibody, TFRC2 antibody, TFR2 antibody, transferrin receptor protein 2 antibody, transferrin receptor 2 antibody|
|Cellular Localization||Cell membrane; Single-pass type II membrane protein , Isoform Beta: Cytoplasm (Probable) |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human TFR2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine|
|Predict Reactivity Note||Mouse (90%), Rat (90%), Bovine (90%)|