|Full Name||transforming growth factor, alpha|
|Product Description||Rabbit Polyclonal antibody to TGF alpha (transforming growth factor, alpha)|
|Background||Transforming growth factors (TGFs) are biologically active polypeptides that reversibly confer the transformed phenotype on cultured cells. TGF-alpha shows about 40% sequence homology with epidermal growth factor (EGF; MIM 131530) and competes with EGF for binding to the EGF receptor (MIM 131550), stimulating its phosphorylation and producing a mitogenic response.[supplied by OMIM]|
|Synonyms||TGFA Antibody, transforming growth factor, alpha Antibody, TFGA Antibody|
|Cellular Localization||Transforming growth factor alpha: Secreted , extracellular space , Protransforming growth factor alpha: Cell membrane; Single-pass type I membrane protein |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TGF alpha. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Pig (100%)|