|Full Name||transforming growth factor, beta receptor III|
|Product Description||Rabbit Polyclonal antibody to TGF beta Receptor III (transforming growth factor, beta receptor III)|
|Background||Transforming growth factor (TGF)-beta is a multifunctional cytokine that modulates several tissue development and repair processes, including cell differentiation, cell cycle progression, cellular migration, adhesion, and extracellular matrix production. Three TGF-beta forms are encoded by separate genes: TGFB1 (MIM 190180), TGFB2 (MIM 190220), and TGFB3 (MIM 190230). The diverse effects of TGF-beta are mediated by the TGF-beta receptors and cell surface-binding proteins. Three TGF-beta receptors exist: type I (TGFBR1; MIM 190181), type II (TFGBR2; MIM 190182), and type III (TGFBR3). TGFBR3 is a glycoprotein that binds TGFB and exists in both a membrane-bound and a soluble form (Johnson et al., 1995 [PubMed 8530052]).[supplied by OMIM]|
|Synonyms||BGCAN antibody, betaglycan antibody, TGFBR3 antibody, transforming growth factor beta receptor type 3 antibody, betaglycan proteoglycan antibody, TGF-beta receptor type 3 antibody, TGF-beta receptor type III antibody, TGFR-3 antibody, "transforming growth factor, beta receptor III antibody"|
|Cellular Localization||Secreted , extracellular space , Cell membrane; Single-pass type I membrane protein (Potential) |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human TGF beta Receptor III. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig|
|Predict Reactivity Note||Mouse (87%), Rat (87%), Pig (89%)|