TGF beta antibody [TB21]
|Applications||ELISA, FACS, IHC-Fr, IHC-P, WB|
| ELISA||Assay-dependent dilution
| Flow cytometry/FACS||Assay-dependent dilution
| IHC (Frozen sections)||Assay-dependent dilution
| IHC (Formalin-fixed paraffin-embedded sections)||Assay-dependent dilution
| Western blot||Assay-dependent dilution
Flow cytometry/FACS : Membrane permeabilisation is required for this application. Use 10μl of the suggested working dilution to label 106 cells in 100μl.Not tested in other applications.
Western blot : This antibody has been demonstrated to react with dimeric (~25 kDa) or monomeric (~12.5 kDa) molecμles of natural TGF-beta1 under non-reducing and reducing conditions respectively.
*Optimal dilutions/concentrations should be determined by the researcher.
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by affinity chromatography|
|Full Name||transforming growth factor beta 1|
|Product Description||Mouse monoclonal antibody [TB21] to TGF beta|
|Background||This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct 2009]|
|Synonyms||LAP Antibody , CED Antibody , TGFB1 Antibody , transforming growth factor, beta 1 Antibody , TGFB Antibody , DPD1 Antibody , TGFbeta Antibody|
|Specificity||This antibody recognizes both human platelet-derived and recombinant TGF-beta1.|
|Immunogen||Human Transforming Growth Factor Beta 1 from platelets.|
|Species Reactivity||Human, Mouse, Rat, Mink, Rabbit, Sheep, Bovine, Mustelid|