|Full Name||THO complex 7 homolog (Drosophila)|
|Product Description||Rabbit Polyclonal antibody to THOC7 (THO complex 7 homolog (Drosophila))|
|Background||Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between THOC4 and the cap-binding protein NCBP1. UAP56 functions as a bridge between THOC4 and the THO complex. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction between KSHV ORF57 protein and THOC4.|
|Synonyms||FLJ23445 antibody, NIF3L1BP1 antibody, fSAP24 antibody, THOC7 antibody, ngg1-interacting factor 3-like protein 1-binding protein 1 antibody, functional spliceosome-associated protein 24 antibody, hTREX30 antibody, Ngg1 interacting factor 3 like 1 binding protein 1 antibody, THO complex subunit 7 homolog antibody, NIF3L1-binding protein 1 antibody, THO complex 7 homolog (Drosophila) antibody|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human THOC7. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Chicken, Bovine|
|Predict Reactivity Note||Rat (97%), Xenopus laevis (82%), Chicken (90%), Bovine (100%)|