APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:500 - 1:1000 |
Assay dependent |
1:1000 - 1:2000 |
Not tested in other applications.
Calculated MW
Product Note
This antibody recognizes human Tie2 in western blot without cross reactivity with human Tie1.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
200 μg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
hTie2 extracellular domain
Purification
Protein G purified
From tissue culture supernatant
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
CD202B , TEK , TEK receptor tyrosine kinase , TIE2 , VMCM , VMCM1
Cellular Localization
Cell membrane,Cell junction,Focal adhesion,Cytoplasm,Cytoskeleton,Secreted
Background
This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]
Database
Research Area
DATA IMAGES
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GTX52471 IHC-P Image
IHC-P analysis of formalin fixed human placenta tissue using GTX52471 TIE2 antibody [21G7].
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REFERENCE
There are currently no references for TIE2 antibody [21G7] (GTX52471). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for TIE2 antibody [21G7] (GTX52471). Be the first to share your experience with this product.