|Full Name||TIMP metallopeptidase inhibitor 1|
|Product Description||Rabbit Polyclonal antibody to TIMP1 (TIMP metallopeptidase inhibitor 1)|
|Background||This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq]|
|Synonyms||CLGI antibody, EPA antibody, EPO antibody, FLJ90373 antibody, HCI antibody, TIMP antibody, TIMP1 antibody, collagenase inhibitor antibody, metalloproteinase inhibitor 1 antibody, erythroid potentiating activity antibody, tissue inhibitor of metalloproteinases 1 antibody, fibroblast collagenase inhibitor antibody, erythroid-potentiating activity antibody, TIMP-1 antibody, TIMP metallopeptidase inhibitor 1 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human TIMP1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Pig, Sheep, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Dog (80%), Pig (85%), Sheep (85%), Rhesus Monkey (99%), Bovine (87%)|