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  • TIMP2 antibody [3A4]

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1 .GTX21828 TIMP2 antibody [3A4]

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TIMP2 antibody [3A4]


  • Host / ClonalityMouse Monoclonal
  • Clone Name3A4
  • ApplicationsIHC-P, WB
  • Species reactivityHuman, Mouse, Rat, Guinea pig, Rabbit, Bovine
  • Publication  ( 3 )
Cat No: GTX21828
Package Price Qty
250 μlUSD 319.00
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  • Anti-TIMP2 antibody [3A4] used in IHC (Formalin-fixed paraffin-embedded sections). GTX21828
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  • Application Information: TIMP2 antibody [3A4]

Catalog Number GTX21828
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( 0 )
Publication ( 3 )
Product Name TIMP2 antibody [3A4]
See all TIMP2 products
ApplicationsIHC-P, WB
Application NoteThis antibody may be diluted to a titer of 1:25-1:50 in an ABC method. We suggest an incubation period of 30 minutes at room temperature. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.
Positive ControlsTestis
Form SuppliedLiquid
PurificationIgG fraction

  • Specifications: TIMP2 antibody [3A4]

Full NameTIMP metallopeptidase inhibitor 2
BackgroundTIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family. TIMPs are of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72 kD Type IV collagenase (MMP-2) and active form of 92 kD Type IV collagenase (MMP-9). TIMPs inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
SynonymsCSC-21K Antibody
Cellular LocalizationCytoplasmic
SpecificityThis antibody is specific for TIMP-2 (21 kDa).
HostMouse
ClonalityMonoclonal
Clone Name3A4
IsotypeIgG2a
ImmunogenBALB/C mice were injected with a synthetic peptide from the N-terminal region of human TIMP 2.
Light Chainkappa
Antigen SpeciesHuman
Species ReactivityHuman, Mouse, Rat, Guinea pig, Rabbit, Bovine
ConjugationUnconjugated

  • Storage Conditions: TIMP2 antibody [3A4]

Storage BufferAntibody solution with sodium azide
Storage InstructionStore at 2-8°C. Do not use beyond the expiration date stated on the label.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Cancer > Type of cancer > Breast > Other
  • Cancer > Type of cancer > Gastrointestinal > Stomach
  • Cancer > Type of cancer > Ovarian
  • Cancer > Type of cancer > Skin > Squamous cell
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TIMP2 antibody [3A4] validated data
  • Anti-TIMP2 antibody [3A4] used in IHC (Formalin-fixed paraffin-embedded sections). GTX21828
    • GTX21828 IHC-P Image
      IHC-P analysis of human pancreas tissue using TIMP2 antibody [3A4].
      Top
  • Anti-TIMP2 antibody [3A4] used in IHC (Formalin-fixed paraffin-embedded sections). GTX21828
    • GTX21828 IHC-P Image
      IHC-P analysis of human pancreas tissue using TIMP2 antibody [3A4].
      Top
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  • Reference for TIMP2 antibody [3A4]
Application References Application Reactivity
Bu S et al. Simulated physiological stretch-induced proliferation of human bladder smooth muscle cells is regulated by MMPs. Arch Biochem Biophys (2014). WB Human
Lin YC et al. Impact of flavonoids on matrix metalloproteinase secretion and invadopodia formation in highly invasive A431-III cancer cells. PLoS One 8 (8):e71903 (2013). WB Human
Corradi D et al. Differential structural remodeling of the left-atrial posterior wall in patients affected by mitral regurgitation with or without persistent atrial fibrillation: a morphological and molecular study. J Cardiovasc Electrophysiol 23 (3):271-9 (2012). IHC-P Human
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