|Full Name||TIMP metallopeptidase inhibitor 3|
|Product Description||Rabbit polyclonal antibody to TIMP3 (TIMP metallopeptidase inhibitor 3)|
|Background||This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq]|
|Synonyms||HSMRK222 antibody, K222 antibody, K222TA2 antibody, SFD antibody, TIMP3 antibody, metalloproteinase inhibitor 3 antibody, tissue inhibitor of metalloproteinases 3 antibody, MIG-5 protein antibody, TIMP-3 antibody, protein MIG-5 antibody, TIMP metallopeptidase inhibitor 3 antibody|
|Cellular Localization||Secreted , extracellular space , extracellular matrix |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human TIMP3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Rat, Xenopus laevis, Dog, Rabbit, Chicken, Sheep, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Human (100%), Rat (97%), Xenopus laevis (83%), Dog (100%), Rabbit (97%), Chicken (82%), Sheep (100%), Rhesus Monkey (100%), Bovine (97%)|