|Full Name||TERF1 (TRF1)-interacting nuclear factor 2|
|Product Description||Rabbit Polyclonal antibody to TIN2 (TERF1 (TRF1)-interacting nuclear factor 2)|
|Background||This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome. [provided by RefSeq]|
|Synonyms||TIN2 antibody, TINF2 antibody, TRF1-interacting nuclear protein 2 antibody, (TRF1)-interacting nuclear factor 2 variant 1 antibody, TERF1-interacting nuclear factor 2 antibody, TERF1 (TRF1)-interacting nuclear factor 2 antibody|
|Cellular Localization||Nucleus , Telomere |
|Immunogen||Full length human TIN2 Recombinant protein.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chimpanzee (99%), Bovine (80%)|