|Full Name||TBP-like 1|
|Product Description||Rabbit Polyclonal antibody to TLP (TBP-like 1)|
|Background||Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes. [provided by RefSeq]|
|Synonyms||MGC:8389 antibody, MGC:9620 antibody, STUD antibody, TLF antibody, TLP antibody, TRF2 antibody, TBPL1 antibody, TATA box-binding protein-related factor 2 antibody, TATA box-binding protein-like protein 1 antibody, TBP-related factor 2 antibody, TBP-related protein antibody, 21-kDA TBP-like protein antibody, second TBP of unique DNA protein antibody, TBP-like 1 antibody|
|Cellular Localization||Cytoplasm (By similarity) , Nucleus |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TLP. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Dog, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (100%), Dog (100%), Chimpanzee (100%), Bovine (100%)|