| Full Name | toll-like receptor 1 |
| Background | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene. [provided by RefSeq, Jul 2008] |
| Synonyms | rsc786 Antibody , TIL. LPRS5 Antibody , toll-like receptor 1 Antibody , TIL Antibody , CD281 Antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | The immunogen corresponding to a region within amino acids 101 and 200 of Human TLR1. |
| Antigen Species | Human |
| Species Reactivity | Human, Mouse, Dog, Rat, Horse, Bovine |
| Conjugation | Unconjugated |