|Full Name||toll like receptor 1|
|Product Description||Rabbit Polyclonal antibody to TLR1 (toll-like receptor 1)|
|Background||The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene. [provided by RefSeq]|
|Synonyms||rsc786 Antibody , TIL Antibody , TIL. LPRS5 Antibody , toll like receptor 1 Antibody , CD281 Antibody|
|Cellular Localization||Cell membrane; Single-pass type I membrane protein (By similarity) , Cytoplasmic vesicle , phagosome membrane; Single-pass type I membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human TLR1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Chimpanzee|
|Predict Reactivity Note||Rhesus Monkey (93%), Chimpanzee (99%)|