|Full Name||toll-like receptor 7|
|Product Description||Rabbit Polyclonal antibody to TLR7 (toll-like receptor 7)|
|Background||The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq]|
|Synonyms||TLR7 antibody, toll-like receptor 7 antibody|
|Cellular Localization||Membrane; Single-pass type I membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human TLR7. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Cat, Pig, Sheep, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (81%), Rat (84%), Dog (82%), Cat (84%), Pig (81%), Sheep (85%), Rhesus Monkey (96%), Chimpanzee (100%), Bovine (86%)|