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1 .GTX13730 TLR7 antibody

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TLR7 antibody


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsFACS, ICC/IF, IHC-Fr, IHC-P, WB
  • Species reactivityHuman, Mouse, Rat
Cat No: GTX13730
Package Price Qty
50 μgUSD 289.00
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  • Anti-TLR7 antibody used in Western Blot (WB). GTX13730
  • Anti-TLR7 antibody used in Flow cytometry/FACS. GTX13730
  • Anti-TLR7 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX13730
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  • Datasheet
  • Application Information: TLR7 antibody

Catalog Number GTX13730
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Product Name TLR7 antibody
See all TLR7 products
ApplicationsFACS, ICC/IF, IHC-Fr, IHC-P, WB
Application NoteWe recommend the following starting dilutions: For WB: Use at a concentration of 1-3 ug/ml. For ICC/IF: Use at a dilution of 1:10-1:2000. For FACS: Use at a concentration of 2-5 ug/ 1x10^6 cells. For IHC-Fr: Use at a dilution of 1:10-1:2000. For IHC-P: Use at a assay dependent dilution. Optimal dilutions should be determined experimentally by the end user.
Positive ControlsHuman Ramos cells
Form SuppliedLiquid
Concentration0.5 mg/ml (Please refer to the vial label for the specific concentration)
PurificationProtein G purified
Purification NoteThis antibody is affinity purified.

  • Specifications: TLR7 antibody

Full Nametoll-like receptor 7
BackgroundThe Toll like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL 1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs characterized so far activate the MyD88/interleukin 1 receptor-associated kinase (IRAK) signaling pathway. Ten human homologs of TLRs (TLR1 10) have been described. Stimulation of the NFkB signaling pathway by TLR7 suggests that it plays a role in immune response.
SynonymsTLR7, Q9NYK1, 300365, 51284
Cellular LocalizationType I membrane protein (By similarity).
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ImmunogenSynthetic peptide: LSHNQLTTVPERLSNCSRSLKNL conjugated to KLH, corresponding to amino acids 706-728 of Human TLR7.
Antigen SpeciesHuman
Species ReactivityHuman, Mouse, Rat
ConjugationUnconjugated

  • Storage Conditions: TLR7 antibody

Storage BufferPBS and 0.05% sodium azide was added as a preservative.
Storage InstructionKeep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Cancer > Type of cancer > Prostate cancer
  • Immunology > Immunodeficiency > HIV Infection
  • Immunology > Immunodeficiency > Toll Like Receptor
  • Immunology > Innate immune response
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TLR7 antibody validated data
  • Anti-TLR7 antibody used in Western Blot (WB). GTX13730
    • GTX13730 WB Image
      Western blot analysis of TLR7 in RAW cell lysate at 3 ug/ml.
      Top
  • Anti-TLR7 antibody used in Flow cytometry/FACS. GTX13730
    • GTX13730 FACS Image
      Intracellular staining by FACS analysis of TLR7 in human PBMC at 0.5 ug/ml. Shaded histogram is cells alone, green is rabbit IgG isotype control, red represents anti-TLR7 antibody. Goat anti-rabbit PE was used for secondary.
      Top
  • Anti-TLR7 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX13730
    • GTX13730 ICC/IF Image
      Immunolocalization of TLR7 (A) and glial fibrillary acidic protein (GFAP) (B) in murine myenteric plexus. Most of the GFAP positive cells were also positive for TLR7 in the merged image (C, yellow staining).
      Top
  • Anti-TLR7 antibody used in Western Blot (WB). GTX13730
    • GTX13730 WB Image
      Western blot analysis of TLR7 in RAW cell lysate at 3 ug/ml.
      Top
  • Anti-TLR7 antibody used in Flow cytometry/FACS. GTX13730
    • GTX13730 FACS Image
      Intracellular staining by FACS analysis of TLR7 in human PBMC at 0.5 ug/ml. Shaded histogram is cells alone, green is rabbit IgG isotype control, red represents anti-TLR7 antibody. Goat anti-rabbit PE was used for secondary.
      Top
  • Anti-TLR7 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX13730
    • GTX13730 ICC/IF Image
      Immunolocalization of TLR7 (A) and glial fibrillary acidic protein (GFAP) (B) in murine myenteric plexus. Most of the GFAP positive cells were also positive for TLR7 in the merged image (C, yellow staining).
      Top
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