|Full Name||transmembrane protein 59|
|Product Description||Rabbit Polyclonal antibody to TMEM59 (transmembrane protein 59)|
|Background||Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding. |
|Synonyms||C1orf8 antibody, FLJ42977 antibody, HSPC001 antibody, TMEM59 antibody, liver membrane-bound protein antibody, transmembrane protein 59 antibody|
|Cellular Localization||Membrane; Single-pass type I membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human TMEM59. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Pig, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Pig (96%), Chicken (84%), Rhesus Monkey (99%), Chimpanzee (100%), Bovine (96%)|