This antibody is directed to different TNF-α epitope than GTX10204 and GTX28348.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Human recombinant tumor necrosis factor of alpha type.
Purification
Protein A purified
Conjugation
Unconjugated
RRID
AB_367832
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]
Indirect ELISA analysis was performed by coating the plate with recombinant 293T expressed, human Fc- tagged TNF alpha(54-233 a.a.) (201.71-3.15 nM). Coated protein was probed with TNF alpha antibody [F6C5] (GTX28349) (1 μg/mL). Please notice that GTX28349 needs to be conjugated to biotin to function as the detection antibody. Please contact us for custom biotin-conjugated antibody.
![Anti-TNF alpha antibody [F6C5] used in ELISA (ELISA). GTX28349](/upload/website/prouct_img/small/GTX28349/GTX28349_45059_20230526_ELISA_Indirect_23053001_612.webp "Anti-TNF alpha antibody [F6C5] used in ELISA (ELISA). GTX28349")
![Anti-TNF alpha antibody [F6C5] used in ELISA (ELISA). GTX28349](/upload/website/prouct_img/normal/GTX28349/GTX28349_45059_20230526_ELISA_Indirect_23053001_612.webp "Anti-TNF alpha antibody [F6C5] used in ELISA (ELISA). GTX28349")