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1 .GTX15563 TNF Receptor II antibody

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TNF Receptor II antibody


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsIHC, IHC-P, IP, WB
  • Species reactivityHuman, Mouse, Rat
  • Publication  ( 1 )
Cat No: GTX15563
Package Price Qty
500 μlUSD 319.00
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  • Anti-TNF Receptor II antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX15563
  • Anti-TNF Receptor II antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX15563
  • Anti-TNF Receptor II antibody used in Immunohistochemistry (IHC). GTX15563
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  • Application Information: TNF Receptor II antibody

Catalog Number GTX15563
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( 0 )
Publication ( 1 )
Product Name TNF Receptor II antibody
See all TNF Receptor II products
ApplicationsIHC, IHC-P, IP, WB
Application NoteIHC-P: Use at a dilution of 1/50 for 30 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. IP: Use at a concentration of 2 μg/ml. WB: Use at a concentration of 1 - 2 μg/ml for 2hrs. Predicted molecular weight: 75 kDa. Optimal dilutions/concentrations should be determined by the end user.
Positive ControlsThymus
Form SuppliedLiquid
Concentration0.2 mg/ml (Please refer to the vial label for the specific concentration)
PurificationImmunogen affinity purified

  • Specifications: TNF Receptor II antibody

Full Nametumor necrosis factor receptor superfamily, member 1b
BackgroundTumor Necrosis Factor (TNF) is a cytokine whose function is mediated through two distinct cell surface receptors (TNFR 1 and TNFR 2) that are included in the TNF receptor superfamily along with FAS antigen and CD40. Tumor necrosis factor receptor 1 and 2 (TNFR 1 and TNFR 2) are 55 and 75 kDa members of a family cell surface molecules including nerve growth factor receptor, Fas/Apo1, CD30, Ox40, and 4-1BB, which are characterized by cysteine rich motifs in the extracellular domain.
SynonymsTnfrsf1b, TNF receptor II, TNF-R-II, TNFR80, TNFR75, Tnfr2, 21938, TNF-R2, TNF-R75, p75, CD120b, TNFBR, Tnfr1, Tnfr-1, TNFRII, TNF R2, Tnfr 1, TNF R75, TNF R II
Cellular LocalizationType I membrane protein and secreted
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ImmunogenSynthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Mouse) (C terminal).
Antigen SpeciesMouse
Species ReactivityHuman, Mouse, Rat
ConjugationUnconjugated

  • Storage Conditions: TNF Receptor II antibody

Storage BufferPhosphate-buffered saline, pH 7.4 containing 1% BSA and 0.09% sodium azide
Storage InstructionKeep as concentrated solution, aliquot and store at 4°C. Do not freeze.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Disease Related > Alzheimer's disease
  • Disease Related > Atherosclerosis
  • Disease Related > Diabetes
  • Neuroscience > Disorder > Alzheimer's disease
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TNF Receptor II antibody validated data
  • Anti-TNF Receptor II antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX15563
    • GTX15563 IHC-P Image
      GTX15563 staining TNF Receptor II at 1/50 dilution in thymus by Immunohistochemistry (FFPE-sections).
      Top
  • Anti-TNF Receptor II antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX15563
    • GTX15563 IHC-P Image
      Human Liver Carcinoma stained with anti-TNF-R2 antibody (GTX15563)
      Top
  • Anti-TNF Receptor II antibody used in Immunohistochemistry (IHC). GTX15563
    • GTX15563 IHC Image
      Top
  • Anti-TNF Receptor II antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX15563
    • GTX15563 IHC-P Image
      GTX15563 staining TNF Receptor II at 1/50 dilution in thymus by Immunohistochemistry (FFPE-sections).
      Top
  • Anti-TNF Receptor II antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX15563
    • GTX15563 IHC-P Image
      Human Liver Carcinoma stained with anti-TNF-R2 antibody (GTX15563)
      Top
  • Anti-TNF Receptor II antibody used in Immunohistochemistry (IHC). GTX15563
    • GTX15563 IHC Image
      Top
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  • Reference for TNF Receptor II antibody
Application References Application Reactivity
Bruggeman LA et al. TNFR2 interposes the proliferative and NF-κB-mediated inflammatory response by podocytes to TNF-α. Lab Invest 91 (3):413-25 (2011). Mouse
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