|Full Name||tumor necrosis factor, alpha-induced protein 3|
|Product Description||Rabbit Polyclonal antibody to A20 (tumor necrosis factor, alpha-induced protein 3)|
|Background||This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. Knockout studies of a similar gene in mice suggested that this gene is critical for limiting inflammation by terminating TNF-induced NF-kappa B responses. [provided by RefSeq]|
|Synonyms||A20 antibody, MGC104522 antibody, MGC138687 antibody, MGC138688 antibody, OTUD7C antibody, TNFA1P2 antibody, TNFAIP3 antibody, tumor necrosis factor inducible protein A20 antibody, TNF alpha-induced protein 3 antibody, OTU domain-containing protein 7C antibody, tumor necrosis factor alpha-induced protein 3 antibody, putative DNA-binding protein A20 antibody, TNFAIP3 (A20) antibody, zinc finger protein A20 antibody, tumor necrosis factor, alpha-induced protein 3 antibody|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human A20. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Pig, Rhesus Monkey|
|Predict Reactivity Note||Mouse (83%), Pig (81%), Rhesus Monkey (97%)|