|Full Name||tumor necrosis factor, alpha-induced protein 8|
|Product Description||Rabbit polyclonal antibody to TNFAIP8 (tumor necrosis factor, alpha-induced protein 8)|
|Background||Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.|
|Synonyms||GG2-1 antibody, MDC-3.13 antibody, SCC-S2 antibody, SCCS2 antibody, TNFAIP8 antibody, TNF-induced protein GG2-1 antibody, NF-kappa-B-inducible DED-containing protein antibody, head and neck tumor and metastasis-related protein antibody, tumor necrosis factor alpha-induced protein 8 antibody, NDED antibody, TNF alpha-induced protein 8 antibody, "tumor necrosis factor, alpha-induced protein 8 antibody"|
|Cellular Localization||Cytoplasm |
|Immunogen||Full length human TNFAIP8 Recombinant protein.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Xenopus laevis, Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (93%), Xenopus laevis (80%), Pig (95%), Chicken (85%), Rhesus Monkey (98%), Bovine (95%)|