|Full Name||tumor necrosis factor receptor superfamily, member 4|
|Product Description||Rabbit Polyclonal antibody to TNFRSF4|
|Background||The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]|
|Synonyms||CD134 Antibody, OX40 Antibody, tumor necrosis factor receptor superfamily, member 4 Antibody, TXGP1L Antibody, ACT35 Antibody|
|Immunogen||KLH conjugated synthetic peptide derived from human TNFRSF4 (101-160aa)|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Bovine, Horse, Dog|