|Full Name||tryptophan hydroxylase 2|
|Product Description||Rabbit Polyclonal antibody to TPH2 (tryptophan hydroxylase 2)|
|Background||This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq]|
|Synonyms||ADHD7 antibody, FLJ37295 antibody, MGC138871 antibody, MGC138872 antibody, NTPH antibody, TPH2 antibody, tryptophan 5-monooxygenase 2 antibody, tryptophan 5-hydroxylase 2 antibody, neuronal tryptophan hydroxylase antibody, tryptophan hydroxylase 2 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human TPH2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Japanese medaka, Dog, Chicken, Rhesus Monkey|
|Predict Reactivity Note||Mouse (97%), Rat (99%), Zebrafish (90%), Japanese medaka (90%), Dog (94%), Chicken (97%), Rhesus Monkey (100%)|