|Full Name||tropomyosin 3|
|Product Description||Rabbit polyclonal antibody to TPM3 (tropomyosin 3)|
|Background||This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||FLJ41118 antibody, MGC14582 antibody, MGC3261 antibody, MGC72094 antibody, NEM1 antibody, OK/SW-cl.5 antibody, TM-5 antibody, TM3 antibody, TM30 antibody, TM30nm antibody, TPMsk3 antibody, TRK antibody, hscp30 antibody, TPM3 antibody, cytoskeletal tropomyosin TM30 antibody, tropomyosin gamma antibody, tropomyosin alpha-3 chain antibody, tropomyosin-3 antibody, tropomyosin-5 antibody, heat-stable cytoskeletal protein 30 kDa antibody, gamma-tropomyosin antibody, tropomyosin 3 antibody|
|Cellular Localization||Cytoplasm , cytoskeleton |
|Immunogen||Full length human TPM3 Recombinant protein.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Dog, Pig, Chicken, Rhesus Monkey|
|Predict Reactivity Note||Mouse (99%), Rat (99%), Zebrafish (83%), Dog (93%), Pig (100%), Chicken (84%), Rhesus Monkey (93%)|