|Full Name||translocated promoter region, nuclear basket protein|
|Product Description||Rabbit Polyclonal antibody to TPR (translocated promoter region, nuclear basket protein)|
|Background||This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias. [provided by RefSeq]|
|Synonyms||translocated promoter region, nuclear basket protein Antibody|
|Cellular Localization||Nucleus , nuclear pore complex , Nucleus membrane; Peripheral membrane protein; Cytoplasmic side |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TPR. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (100%), Bovine (100%)|