|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||80 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||TNF receptor-associated protein 1|
|Product Description||Rabbit Polyclonal antibody to TRAP1 (TNF receptor-associated protein 1)|
|Background||HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. TRAP1 is a mitochondrial HSP90 protein. Other HSP90 proteins are found in cytosol (see HSP90AA1; MIM 140571) and endoplasmic reticulum (HSP90B1; MIM 191175) (Chen et al., 2005 [PubMed 16269234]).[supplied by OMIM]|
|Synonyms||HSP75 antibody, HSP90L antibody, TRAP1 antibody, "heat shock protein 75 kDa, mitochondrial antibody", TRAP-1 antibody, tumor necrosis factor type 1 receptor-associated protein antibody, HSP 75 antibody, tumor necrosis factor type 1 receptor associated protein antibody, TNFR-associated protein 1 antibody, TNF receptor-associated protein 1 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human TRAP1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Chicken, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (91%), Pig (89%), Chicken (85%), Chimpanzee (99%), Bovine (90%)|