| Full Name | TAR (HIV-1) RNA binding protein 1 |
| Product Description | Rabbit polyclonal antibody to TRBP1 |
| Background | The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1alpha (EF-1alpha), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation. |
| Synonyms | TRBP1, TARBP1, TRP-185, TRP185, TRP-1, TRP1, TAR RNA binding protein1, TAR RNA binding protein 1, TRP 1, TRP 185 |
| Specificity | This antibody is specific for TRBP1 Internal |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target | TRBP1 |
| Species Reactivity | Human, Mouse |