TRF1 antibody [C3], C-term
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||50 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||telomeric repeat binding factor (NIMA-interacting) 1|
|Product Description||Rabbit polyclonal antibody to TRF1 (telomeric repeat binding factor (NIMA-interacting) 1)|
|Background||This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products. [provided by RefSeq]|
|Synonyms||FLJ41416 antibody, PIN2 antibody, TRBF1 antibody, TRF antibody, TRF1 antibody, hTRF1-AS antibody, t-TRF1 antibody, TERF1 antibody, telomeric repeat-binding factor 1 antibody, NIMA-interacting protein 2 antibody, telomeric protein Pin2/TRF1 antibody, TTAGGG repeat-binding factor 1 antibody, telomeric repeat binding factor (NIMA-interacting) 1 antibody|
|Cellular Localization||Nucleus , Spindle , Telomere |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TRF1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (93%)|