|Full Name||tripartite motif containing 23|
|Product Description||Rabbit Polyclonal antibody to TRIM23 (tripartite motif containing 23)|
|Background||The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. [provided by RefSeq]|
|Synonyms||ARD1 antibody, ARFD1 antibody, RNF46 antibody, TRIM23 antibody, "ADP-ribosylation factor domain protein 1, 64kDa antibody", E3 ubiquitin-protein ligase TRIM23 antibody, ARF domain protein 1 antibody, ADP-ribosylation factor domain-containing protein 1 antibody, GTP-binding protein ARD-1 antibody, tripartite motif-containing 23 antibody, tripartite motif-containing protein 23 antibody, RING finger protein 46 antibody, tripartite motif protein TRIM23 antibody, tripartite motif containing 23 antibody|
|Cellular Localization||Endomembrane system , Golgi apparatus membrane , Lysosome membrane |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human TRIM23. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rhesus Monkey (100%)|