|Applications||ICC/IF, IP, WB|
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||58 kDa (note)
|Positive Controls||K562 , THP-1 , HL-60 , U87-MG , SK-N-SH , IMR32 , rat testis|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||tripartite motif containing 27|
|Product Description||Rabbit Polyclonal antibody to TRIM27 (tripartite motif containing 27)|
|Background||This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein. [provided by RefSeq]|
|Synonyms||RFP antibody, RNF76 antibody, TRIM27 antibody, tripartite motif protein TRIM27 antibody, zinc finger protein RFP antibody, RFP transforming protein antibody, RING finger protein 76 antibody, tripartite motif-containing protein 27 antibody, tripartite motif-containing 27 antibody, ret finger protein antibody, tripartite motif containing 27 antibody|
|Cellular Localization||Nucleus (By similarity) , Cytoplasm (By similarity) |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human TRIM27. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rhesus Monkey (100%), Bovine (99%)|