|Full Name||tripartite motif containing 3|
|Product Description||Rabbit polyclonal antibody to TRIM3 (tripartite motif-containing 3)|
|Background||The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified. [provided by RefSeq]|
|Synonyms||BERP antibody, FLJ16135 antibody, HAC1 antibody, RNF22 antibody, RNF97 antibody, TRIM3 antibody, brain expressed ring finger antibody, RING finger protein 97 antibody, brain-expressed RING finger protein antibody, tripartite motif-containing protein 3 antibody, ring finger protein 22 antibody, tripartite motif-containing 3 antibody, tripartite motif protein TRIM3 antibody, tripartite motif containing 3 antibody|
|Cellular Localization||Cytoplasm (By similarity) , Early endosome |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human TRIM3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (100%), Rat (100%), Rhesus Monkey (100%), Bovine (100%)|