|Full Name||transient receptor potential cation channel, subfamily C, member 6|
|Product Description||Rabbit Polyclonal antibody to TRPC6 (transient receptor potential cation channel, subfamily C, member 6)|
|Background||The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq]|
|Synonyms||FLJ11098 antibody, FLJ14863 antibody, FSGS2 antibody, TRP6 antibody, TRPC6 antibody, short transient receptor potential channel 6 antibody, TRP-6 antibody, transient receptor protein 6 antibody, "transient receptor potential cation channel, subfamily C, member 6 antibody"|
|Cellular Localization||Membrane; Multi-pass membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human TRPC6. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine, Guinea pig|
|Predict Reactivity Note||Mouse (85%), Rat (88%), Bovine (91%), Guinea pig (91%)|