|Full Name||transient receptor potential cation channel, subfamily C, member 4 associated protein|
|Product Description||Rabbit Polyclonal antibody to TRPC4AP (transient receptor potential cation channel, subfamily C, member 4 associated protein)|
|Background||Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.|
|Synonyms||C20orf188 antibody, TRRP4AP antibody, TRUSS antibody, TRPC4AP antibody, TRP4-associated protein antibody, short transient receptor potential channel 4-associated protein antibody, trpc4-associated protein antibody, short transient receptor potential channel 4 associated protein antibody, tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein antibody, TNF-receptor ubiquitous scaffolding/signaling protein antibody, "transient receptor potential cation channel, subfamily C, member 4 associated protein antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human TRUSS. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Chicken, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Xenopus laevis (83%), Chicken (83%), Bovine (100%)|