|Full Name||tumor necrosis factor, alpha-induced protein 6|
|Product Description||Rabbit polyclonal antibody to TSG-6 (tumor necrosis factor, alpha-induced protein 6)|
|Background||The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. The expression of this gene can be induced by tumor necrosis factor alpha and interleukin-1. The expression can also be induced by mechanical stimuli in vascular smooth muscle cells, and is found to be correlated with proteoglycan synthesis and aggregation. [provided by RefSeq]|
|Synonyms||TSG-6 antibody, TSG6 antibody, TNFAIP6 antibody, TNF alpha-induced protein 6 antibody, tumor necrosis factor-inducible gene 6 protein antibody, TNF-stimulated gene 6 protein antibody, tumor necrosis factor-stimulated gene-6 protein antibody, tumor necrosis factor alpha-inducible protein 6 antibody, hyaluronate-binding protein antibody, "tumor necrosis factor, alpha-induced protein 6 antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human TSG-6. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Pig, Rabbit, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (93%), Rat (92%), Pig (93%), Rabbit (95%), Chicken (86%), Rhesus Monkey (95%), Bovine (95%)|