TXNDC4 antibody [C1C3]
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||47 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||endoplasmic reticulum protein 44|
|Product Description||Rabbit Polyclonal antibody to TXNDC4 (endoplasmic reticulum protein 44)|
|Background||Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.|
|Synonyms||KIAA0573 antibody, PDIA10 antibody, TXNDC4 antibody, ERP44 antibody, ER protein 44 antibody, endoplasmic reticulum resident protein 44 antibody, thioredoxin domain-containing protein 4 antibody, "protein disulfide isomerase family A, member 10 antibody", endoplasmic reticulum resident protein 44 kDa antibody, thioredoxin domain containing 4 (endoplasmic reticulum) antibody, endoplasmic reticulum protein 44 antibody|
|Cellular Localization||Endoplasmic reticulum lumen |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human TXNDC4. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Xenopus laevis, Pig, Bovine|
|Predict Reactivity Note||Mouse (98%), Rat (99%), Zebrafish (83%), Xenopus laevis (83%), Pig (97%), Bovine (97%)|