TXNL2 antibody [N2C3]
|Applications||ICC/IF, IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||37 kDa (note)
|Positive Controls||293T , A431 , Jurkat , Raji , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||glutaredoxin 3|
|Product Description||Rabbit Polyclonal antibody to TXNL2 (glutaredoxin 3)|
|Background||This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq]|
|Synonyms||FLJ11864 antibody, GLRX4 antibody, GRX3 antibody, GRX4 antibody, PICOT antibody, TXNL2 antibody, TXNL3 antibody, GLRX3 antibody, PKC-theta-interacting protein antibody, PKC-interacting cousin of thioredoxin antibody, thioredoxin-like protein 2 antibody, glutaredoxin 4 antibody, PKCq-interacting protein antibody, glutaredoxin-3 antibody, glutaredoxin 3 antibody|
|Cellular Localization||Cytoplasm , cell cortex |
|Specificity||Knockdown/Knockout validation was supported by references (PMID:26991013)|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human TXNL2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Pig, Chicken, Bovine|
|Predict Reactivity Note||Rat (96%), Xenopus laevis (80%), Pig (94%), Chicken (86%), Bovine (96%)|