|Full Name||tyrosine kinase 2|
|Product Description||Rabbit Polyclonal antibody to TYK2 (tyrosine kinase 2)|
|Background||This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq]|
|Synonyms||JTK1 antibody, TYK2 antibody, non-receptor tyrosine-protein kinase TYK2 antibody, tyrosine kinase 2 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human TYK2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Pig (84%), Bovine (85%)|