Talin-1 antibody [C3], C-term
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||270 kDa (note)
|Positive Controls||Neuro2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12 , A549 , H1299 , HCT116|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||talin 1|
|Product Description||Rabbit Polyclonal antibody to Talin-1 (talin 1)|
|Background||This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. [provided by RefSeq]|
|Synonyms||ILWEQ antibody, KIAA1027 antibody, TLN antibody, TLN1 antibody, talin-1 antibody, talin 1 antibody|
|Cellular Localization||Cell projection , ruffle membrane; Peripheral membrane protein; Cytoplasmic side (By similarity) , Cytoplasm , cytoskeleton (By similarity) |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human Talin 1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Chicken, Bovine|
|Predict Reactivity Note||Rat (99%), Zebrafish (92%), Chicken (93%), Bovine (100%)|