Tara antibody [C2C3-2], C-term
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||261 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , Rat2|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||TRIO and F-actin binding protein|
|Product Description||Rabbit Polyclonal antibody to Tara (TRIO and F-actin binding protein)|
|Background||This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD). [provided by RefSeq]|
|Synonyms||DFNB28 antibody, FLJ39315 antibody, KIAA1662 antibody, TARA antibody, dJ37E16.4 antibody, TRIOBP antibody, TRIO and F-actin-binding protein antibody, tara-like protein antibody, trio-associated repeat on actin antibody, protein Tara antibody, TRIO and F-actin binding protein antibody|
|Cellular Localization||Nucleus , Cytoplasm , cytoskeleton |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Tara. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (89%)|