|Full Name||microtubule-associated protein tau|
|Product Description||Rabbit Polyclonal antibody to Tau (microtubule-associated protein tau)|
|Background||This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq]|
|Synonyms||DDPAC antibody, FLJ31424 antibody, FTDP-17 antibody, MAPTL antibody, MGC138549 antibody, MSTD antibody, MTBT1 antibody, MTBT2 antibody, PPND antibody, TAU antibody, MAPT antibody, microtubule-associated protein tau, isoform 4 antibody, G protein beta1/gamma2 subunit-interacting factor 1 antibody, microtubule-associated protein tau antibody, neurofibrillary tangle protein antibody, PHF-tau antibody, paired helical filament-tau antibody|
|Cellular Localization||Cytoplasm , cytosol , Cell membrane; Peripheral membrane protein; Cytoplasmic side , cytoskeleton , Cell projection , axon |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Tau. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Dog (94%), Chimpanzee (94%)|