|Full Name||deoxynucleotidyltransferase, terminal|
|Product Description||Rabbit polyclonal antibody to TdT (deoxynucleotidyltransferase, terminal)|
|Background||This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq]|
|Synonyms||TDT antibody, DNTT antibody, terminal addition enzyme antibody, terminal transferase antibody, DNA nucleotidylexotransferase antibody, terminal deoxynucleotidyltransferase antibody, terminal deoxyribonucleotidyltransferase antibody, nucleosidetriphosphate:DNA deoxynucleotidylexotransferase antibody, "deoxynucleotidyltransferase, terminal antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human TdT. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (80%), Rat (82%), Rhesus Monkey (98%), Bovine (88%)|