|Full Name||titin-cap (telethonin)|
|Product Description||Rabbit polyclonal antibody to Telethonin (titin-cap (telethonin))|
|Background||Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq]|
|Synonyms||CMD1N antibody, LGMD2G antibody, T-cap antibody, TELE antibody, telethonin antibody, TCAP antibody, limb girdle muscular dystrophy 2G (autosomal recessive) antibody, titin cap protein antibody, 19 kDa sarcomeric protein antibody, titin-cap (telethonin) antibody|
|Cellular Localization||Cytoplasm , myofibril , sarcomere |
|Immunogen||Full length human Telethonin Recombinant protein.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Dog, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (91%), Dog (90%), Pig (92%), Rhesus Monkey (98%), Bovine (94%)|