|Full Name||serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7|
|Product Description||Rabbit Polyclonal antibody to Thyroxine Binding Globulin (serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7)|
|Background||There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3 -triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.|
|Synonyms||FLJ17820 antibody, TBG antibody, SERPINA7 antibody, T4-binding globulin antibody, thyroxine-binding globulin antibody, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 antibody, thyroxin-binding globulin antibody, serpin A7 antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 antibody|
|Cellular Localization||Secreted |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Thyroxine Binding Globulin. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Pig, Sheep, Chimpanzee, Bovine|
|Predict Reactivity Note||Pig (85%), Sheep (85%), Chimpanzee (100%), Bovine (86%)|