TORC2 (phospho Ser171) antibody
|Applications||ELISA, ICC/IF, IHC-F, IHC-P, IP, WB|
|Application Note||WB(1:100-500), ELISA(1:500-1000), IP(1:20-100), IHC-P(1:100-500), IHC-F(1:100-500), IF(1:100-500)|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by Protein A and peptide affinity chromatography.|
|Full Name||CREB regulated transcription coactivator 2|
|Product Description||Rabbit Polyclonal antibody to TORC2 (phospho Ser171)|
|Background||This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010]|
|Synonyms||Torc2 (phospho Ser171) (pSer171) Antibody, Torc2 (phospho Ser171) (Phospho Ser171) Antibody, Phospho Torc2 (phospho Ser171) (pSer171) Antibody, Phospho Torc2 (phospho Ser171) (Ser171) Antibody, Torc2 (phospho Ser171) (Phospho S171) Antibody, Phospho Torc2|
|Target||TORC2 (phospho Ser171)|
|Immunogen||KLH conjugated Synthesised phosphopeptide derived from human TORC2 around the phosphorylation site of Ser171|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.