|Full Name||transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)|
|Product Description||Rabbit Polyclonal antibody to Transglutaminase 2 (transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase))|
|Background||Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||G-ALPHA-h antibody, GNAH antibody, TG2 antibody, TGC antibody, TGM2 antibody, C polypeptide antibody, TGase-2 antibody, transglutaminase-2 antibody, TG(C) antibody, TGase H antibody, protein-glutamine-gamma-glutamyltransferase antibody, protein-glutamine gamma-glutamyltransferase 2 antibody, tissue transglutaminase antibody, transglutaminase C antibody, transglutaminase H antibody, TGase C antibody, TGase-H antibody, "transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Transglutaminase 2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Bovine, Guinea pig|
|Predict Reactivity Note||Rat (82%), Bovine (88%), Guinea pig (83%)|