TrkC antibody [N2C1], Internal
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||94 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , Molt-4 , Raji , NIH-3T3|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||neurotrophic tyrosine kinase, receptor, type 3|
|Product Description||Rabbit polyclonal antibody to TrkC (neurotrophic tyrosine kinase, receptor, type 3)|
|Background||This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. [provided by RefSeq]|
|Synonyms||TRKC antibody, gp145(trkC) antibody, NTRK3 antibody, ETS related protein-neurotrophic receptor tyrosine kinase fusion protein antibody, ETV6-NTRK3 fusion antibody, NT-3 growth factor receptor antibody, tyrosine kinase receptor C antibody, GP145-TrkC antibody, "neurotrophic tyrosine kinase, receptor, type 3 antibody"|
|Cellular Localization||Membrane; Single-pass type I membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human TrkC. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (91%), Pig (94%), Chicken (82%), Rhesus Monkey (100%), Chimpanzee (99%), Bovine (92%)|