|Full Name||troponin T type 1 (skeletal, slow)|
|Product Description||Rabbit Polyclonal antibody to Troponin T1 (slow skeletal) (troponin T type 1 (skeletal, slow))|
|Background||This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||ANM antibody, FLJ98147 antibody, MGC104241 antibody, STNT antibody, TNT antibody, TNTS antibody, TNNT1 antibody, "troponin T, slow skeletal muscle antibody", "troponin-T1, skeletal, slow antibody", slow skeletal muscle troponin T antibody, "troponin T type 1 (skeletal, slow) antibody"|
|Immunogen||Full length human Troponin T1 (slow skeletal) Recombinant protein.|
|Species Reactivity||Human, Pig|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (92%)|