|Full Name||tyrosinase (oculocutaneous albinism IA)|
|Product Description||Rabbit Polyclonal antibody to Tyrosinase (tyrosinase (oculocutaneous albinism IA))|
|Background||The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq]|
|Synonyms||CMM8 antibody, OCA1A antibody, OCAIA antibody, SHEP3 antibody, TYR antibody, tumor rejection antigen AB antibody, monophenol monooxygenase antibody, LB24-AB antibody, tyrosinase antibody, SK29-AB antibody, tyrosinase (oculocutaneous albinism IA) antibody|
|Cellular Localization||Melanosome membrane; Single-pass type I membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Tyrosinase. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Pig, Rabbit, Sheep, Bovine|
|Predict Reactivity Note||Mouse (90%), Rat (92%), Dog (90%), Pig (94%), Rabbit (92%), Sheep (92%), Bovine (92%)|