Tyrosine Hydroxylase antibody [N1C1]
|Applications||ICC/IF, IHC-Fr, IHC-P, WB, IHC-Wm|
Not tested in other applications.
|IHC (Frozen sections)||1:100-1:1000*
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
|IHC (Whole mount)||1:100-1:500*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||59 kDa (note)
|Positive Controls||IMR32 , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||tyrosine hydroxylase|
|Product Description||Rabbit polyclonal antibody to Tyrosine Hydroxylase (tyrosine hydroxylase)|
|Background||The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq]|
|Synonyms||DYT14 antibody, DYT5b antibody, TYH antibody, TH antibody, dystonia 14 antibody, tyrosine 3-hydroxylase antibody, tyrosine 3-monooxygenase antibody, tyrosine hydroxylase antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Tyrosine Hydroxylase. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (87%)|