|Full Name||U2 small nuclear RNA auxiliary factor 2|
|Product Description||Rabbit Polyclonal antibody to U2AF65 (U2 small nuclear RNA auxiliary factor 2)|
|Background||U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date. [provided by RefSeq]|
|Synonyms||U2AF65 antibody, U2AF2 antibody, hU2AF(65) antibody, splicing factor U2AF 65 kD subunit antibody, hU2AF65 antibody, splicing factor U2AF 65 kDa subunit antibody, U2 snRNP auxiliary factor large subunit antibody, U2 small nuclear ribonucleoprotein auxiliary factor (65kD) antibody, U2 (RNU2) small nuclear RNA auxiliary factor 2 antibody, U2 auxiliary factor 65 kDa subunit antibody, U2 small nuclear RNA auxiliary factor 2 antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human U2AF65. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Xenopus laevis, Pig, Bovine|
|Predict Reactivity Note||Mouse (100%), Xenopus laevis (96%), Pig (100%), Bovine (99%)|