|Full Name||ubiquitin-conjugating enzyme E2B (RAD6 homolog)|
|Product Description||Rabbit Polyclonal antibody to UBE2B (ubiquitin-conjugating enzyme E2 B)|
|Background||The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. [provided by RefSeq]|
|Synonyms||E2-17kDa antibody, HHR6B antibody, HR6B antibody, RAD6B antibody, UBC2 antibody, UBE2B antibody, ubiquitin-protein ligase B antibody, ubiquitin carrier protein B antibody, ubiquitin-conjugating enzyme E2-17 kDa antibody, ubiquitin-conjugating enzyme E2 B antibody, RAD6 homolog B antibody, ubiquitin-conjugating enzyme E2B (RAD6 homolog) antibody, E2 protein antibody|
|Cellular Localization||Cell membrane (By similarity) , Nucleus (By similarity) |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human UBE2B. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Pig, Rabbit, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (100%), Zebrafish (95%), Xenopus laevis (98%), Pig (100%), Rabbit (100%), Rhesus Monkey (100%), Bovine (100%)|